Clinical trial to assess the removal of filter ventilation on smoking behavior and biomarkers

What is the purpose of the study?

This study will examine how the design of the cigarette filter affects smoking behavior, exposure to smoke chemicals and the potential health effects from these exposures. The health measures that we examine include exposure to tobacco chemicals, nicotine levels, and risk factors for lung or heart disease. The cigarette used in this study is a brand of cigarettes that you can buy at the store.

How often are the clinic visits?

You will first attend a screening visit to see if you are eligible. The research study lasts about 15 weeks. You will attend weekly visits for 11 weeks and then a follow-up visit 1 month after you stop the study cigarettes. The visits last between 1-3 hours.

What will I be doing in the study?

You will be asked to complete questionnaires and a breath test for carbon monoxide. Cells from your mouth, saliva and urine samples will be collected from you. You will keep daily record of your tobacco use. Lastly, you will exchange points for study products including cigarettes and possibly other nicotine containing products.

Will I be compensated?

If you agree to take part in this research study, you could receive up to $650 for your time and effort. You will receive $20 for attending each of the longer clinic visits (10 visits), and $10 for travel. At each of the shorter visits (2 visits) where you receive product only, you will only receive $10 for travel. In addition you will receive an additional $15 for the 4 visits where we collect samples. At the end of the study you will receive $10 for each week that you completed all of the daily calls. If you have completed all other study procedures you will receive a $130 bonus at the end of the study.

What should I do if I'm interested?

If you would like to find out if you qualify for this study contact us at 612-624-5350 or email Please leave your name and a contact number in your email or voicemail. 

We are looking for...

Men and women who are regular tobacco users, ages 18 and up and are generally healthy.

Study Coordinator

If you would like to find out if you qualify for this study please call 612-624-5350 or email


Tobacco Research Programs
717 Delaware St SE
Minneapolis, MN 55414

Phone: 612-626-5155
Fax: 612-624-4610